When it comes to healthcare, comfort is not a luxury—it’s a necessity. Healthcare professionals spend long hours on their feet, responding to emergencies, assisting patients, and managing demanding workloads. Comfortable medical scrubs can make a significant difference in overall performance, posture, and morale. In 2025, advancements in fabric technology, design, and functionality have redefined what comfort in scrubs really means. Whether you're a nurse, doctor, or allied health professional, finding the right scrubs can enhance both your comfort and confidence.

Here’s a list of the top 10 most comfortable medical scrubs for long shifts in 2025, with several options available for those specifically looking for nursing scrubs in Australia.

1. Figs Yola Skinny Scrub Pants + Casma Three-Pocket Top

Figs has become synonymous with stylish and comfortable medical scrubs. Their proprietary FIONx fabric offers four-way stretch, moisture-wicking properties, and anti-wrinkle technology. The Yola pants and Casma top are designed for a flattering fit without compromising on mobility. Popular among nurses and doctors alike, Figs is a strong contender globally and in Australia.

2. Cherokee Infinity Collection

Cherokee has long been a trusted brand in the healthcare apparel space. The Infinity line stands out in 2025 for its soft, stretchy fabric that combines polyester, rayon, and spandex. The antimicrobial finish and breathable panels make these scrubs ideal for long hospital shifts.

3. Jaanuu Signature Gold Label Scrubs

Jaanuu has gained popularity due to its fashion-forward medical scrubs that don’t skimp on comfort. Their Signature Gold Label line includes scrubs made from proprietary SPINryx™ fabric, which offers superior stretch, breathability, and odor control. These scrubs are especially popular among younger healthcare workers looking for a blend of style and function.

4. Barco One Wellness Scrubs

Barco One Wellness scrubs are known for their eco-conscious design and comfort-driven features. The use of recycled materials doesn’t compromise softness or durability. They offer thermoregulation and soil release properties—ideal for high-pressure, fast-paced healthcare settings.

5. Skechers by Barco

Skechers is no longer just about shoes. Their partnership with Barco has resulted in scrubs that combine lightweight, moisture-wicking fabric with sporty design. These scrubs are particularly beneficial for professionals looking for flexible, durable clothing that holds up during high-energy shifts.

6. Grey’s Anatomy Stretch Collection

Inspired by the hit medical drama, the Grey’s Anatomy Stretch line is more than just a name. With four-way stretch and a silky finish, these scrubs feel luxurious while offering the practical features healthcare workers need—like deep pockets and breathable fabric. It’s a popular choice in both urban hospitals and regional practices.

7. Medelita Insight Scrubs

Medelita has carved a niche in premium healthcare wear, and their Insight line represents the pinnacle of comfort. Designed for medical professionals who prioritize performance, these scrubs are resistant to fading, pilling, and shrinking—making them ideal for extended use over time.

8. WonderWink PRO Scrubs

WonderWink’s PRO collection is tailored for maximum movement and durability. With a unique polyester-rayon-spandex blend, these scrubs are soft yet structured, making them suitable for all body types. They’re especially popular in clinical and aged care settings across Australia.

9. Healing Hands Purple Label Scrubs

Healing Hands is a brand beloved for its attention to detail and luxurious fabrics. The Purple Label line features high-quality rayon blends that provide both softness and structure. These scrubs are favored by nurses and midwives who require both elegance and endurance in their workwear.

10. Biz Care Antibacterial Scrubs (Australia-Specific Pick)

For those seeking nursing scrubs in Australia, Biz Care offers a standout local option. Their antibacterial scrubs are designed with Australian healthcare professionals in mind. Made from durable, easy-care fabrics with an emphasis on infection control, these scrubs combine practicality with modern design aesthetics. They’re lightweight, breathable, and built to last through even the most demanding rosters.

What to Look for in Comfortable Medical Scrubs

When choosing medical scrubs for long shifts, prioritize fabric composition, breathability, fit, and the number of functional features such as pockets or stretch panels. Avoid scrubs that restrict movement or lack ventilation, especially in warmer climates or high-stress environments.

It's also worth considering antimicrobial and moisture-wicking properties, which are particularly relevant in today's post-pandemic healthcare landscape. As more professionals shift to online ordering, many suppliers of nursing scrubs in Australia offer virtual fittings, customer reviews, and flexible return policies to ensure the best fit and comfort.

Conclusion

In 2025, the line between comfort and performance in medical attire continues to blur, with brands pushing the limits of design, function, and durability. Whether you prefer well-established global names or are seeking homegrown Australian brands, the right pair of scrubs can elevate your daily experience in a profound way. For the best blend of style, comfort, and quality, these top 10 options are well worth considering. As the demand grows, so does the innovation in scrubs clothing in Australia, ensuring healthcare professionals stay at the top of their game, comfortably.